Example: bipolar_cell

Note

You can launch an interactive, editable version of this example without installing any local files using the Binder service (although note that at some times this may be slow or fail to open): launchbinder

A pseudo MSO neuron, with two dendrites and one axon (fake geometry).

from brian2 import *

# Morphology
morpho = Soma(30*um)
morpho.axon = Cylinder(diameter=1*um, length=300*um, n=100)
morpho.L = Cylinder(diameter=1*um, length=100*um, n=50)
morpho.R = Cylinder(diameter=1*um, length=150*um, n=50)

# Passive channels
gL = 1e-4*siemens/cm**2
EL = -70*mV
eqs='''
Im = gL * (EL - v) : amp/meter**2
I : amp (point current)
'''

neuron = SpatialNeuron(morphology=morpho, model=eqs,
                       Cm=1*uF/cm**2, Ri=100*ohm*cm, method='exponential_euler')
neuron.v = EL
neuron.I = 0*amp

# Monitors
mon_soma = StateMonitor(neuron, 'v', record=[0])
mon_L = StateMonitor(neuron.L, 'v', record=True)
mon_R = StateMonitor(neuron, 'v', record=morpho.R[75*um])

run(1*ms)
neuron.I[morpho.L[50*um]] = 0.2*nA  # injecting in the left dendrite
run(5*ms)
neuron.I = 0*amp
run(50*ms, report='text')

subplot(211)
plot(mon_L.t/ms, mon_soma[0].v/mV, 'k')
plot(mon_L.t/ms, mon_L[morpho.L[50*um]].v/mV, 'r')
plot(mon_L.t/ms, mon_R[morpho.R[75*um]].v/mV, 'b')
ylabel('v (mV)')
subplot(212)
for x in linspace(0*um, 100*um, 10, endpoint=False):
    plot(mon_L.t/ms, mon_L[morpho.L[x]].v/mV)
xlabel('Time (ms)')
ylabel('v (mV)')
show()
../_images/compartmental.bipolar_cell.1.png